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Rosuvastatin Calcium manufacturer CAS:147098-20-2

Sep 10th, 2022 at 04:23   Electronic Chemicals   Naperville   50 views Reference: K4oeElwgd0B

Location: Naperville

Price: Contact us


Synonyms:
(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt
Rosuvastatin Calcium Salt
Rosuvastatin Hemicalcium
ZD 4522 Calcium Salt
Rosuvastatin Calcium
Molecular Formula: C44H54CaF2N6O12S2
Molecular Weight: 1001.14000

Appearance and properties: white to off-white crystalline solid
Boiling point: 745.6ºC at 760 mmHg
Melting point: 122ºC
Flash point: 404.7ºC

Storage conditions: -20°C Freezer
use:Lipid-lowering drugs.


Items of Analysis Standard of Analysis Test Results
Appearance Off-white to pale yellow powder Off-white powder
Specific rotation(° +13.0~+18.0 +17.9
Identification IR Consistent with the reference Consistent with the reference
Calcium salt Positive response Positive response
GC The main peak retention time consistent with thereference The main peak retention time consistent with thereference
Water
(%,w/w)
≤3.0 2.5
Loss on drying
(%,w/w)
≤3.0 1.7
Relative Substance
(%,area,HPLC)
Single impurity ≤0.10 <0.05
Total impurity ≤1.0 <0.05
Diastereomer
(EP Imp.B)
≤0.15 <0.05
EP Imp.A ≤0.10 Not detected
5-Keto acid
(EP Imp.C)
≤0.10 <0.05
Assay
(%, ESTD, HPLC)
98.0-102.0 99.7
Conclusion ConformstoFactory Standard



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