CAS No: 497-76-7
Product Name: Arbutin
Other Name:
Arbutin
hydroquinone O-β-D-glucopyranoside
4-Hydroxyphenyl β-D-glucopyranoside
Hydroquinone-β-D-glucopyranoside
(2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol
Density: 1.6±0.1 g/cm3
Boiling Point: 561.6±50.0 °C at 760 mmHg
Melting Point: 195-198 °C
Molecular Formula: C12H16O7
Molecular Weight: 272.251
Flash Point: 293.4±30.1 °C
Exact Mass: 272.089600
PSA: 119.61000
LogP: -1.35
Vapour Pressure: 0.0±1.6 mmHg at 25°C
Index of Refraction: 1.650
Water Solubility: 10-15 g/100 mL at 20 ºC
Specification
Appearance: White Crystalline powder
Assay: ≥99.5%
Melting point: 199~201±0.5℃
Clarity of water solution: Transpency,colorless,non suspended matters
pH value of 1% aqueous solution: 5.0~7.0
Specific optical ratation: 【a】D20=-66±2°
Arsenic: ≤2ppm
Hydroquinone: ≤10ppm
Heavy metals: ≤10ppm
Loss on drying: ≤0.5%
Residue on ignition: ≤0.5%
Pathogen
Bacteria: ≤300cfu/g
Fungus: ≤100cfu/g
Application
1. Anti-inflammatory and bacteriostatic effect: Arbutin has anti-inflammatory and bacteriostatic effects. It is traditionally used to treat urinary tract infections, among which arbutin is its main medicinal ingredient.
2. Antitussive, expectorant, and asthma: Arbutin gavage can increase animal tracheal secretion, prolong the incubation period of ammonia-induced cough, reduce the number of coughs, and significantly increase the amount of phenol red excretion in the trachea. But so far, its anti-inflammatory, antitussive and expectorant mechanisms have not been reported.
3. Whitening and depigmentation: Arbutin is a skin lightening active derived from natural plants. It can penetrate into the skin quickly, while not affecting the proliferation concentration of skin cells, it can effectively inhibit the activity of tyrosinase in the skin, block the formation of melanin, and accelerate the decomposition and excretion of melanin through its combination with tyrosinase. , Thereby reducing skin pigmentation and removing pigmentation and freckles. It does not produce toxic, irritating, allergenic and other side effects on melanin cells, but also has emollient, trauma, bactericidal and synergistic anti-inflammatory effects. It is one of the safest and most effective whitening ingredients popular in foreign countries, and it is also the most competitive skin whitening and freckle active agent in the 21st century.
Package: 25kg/drum, can also be designed according to customer requirements.
Storage: Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
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Inno Pharmchem (Pharmaceutical Intermediates Manufacturers in China) is exclusively focusing on the manufacturing of API's Intermediates, such as Arbutin, cas:497-76-7 , Hydroquinone-β-D-glucopyranoside and so on. We have helped clients businesses by scaling up its pharmaceutical products through the development of innovative processes and optimizing the production process thus it making it cost-efficient.
Keywords: Hydroquinone-β-D-glucopyranoside manufacturer;Arbutin factory;(2R3S4S5R6S)-2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2H-pyran-345-triol producer;hydroquinone O-β-D-glucopyranoside vendor;4-Hydroxyphenyl β-D-glucopyranoside supplier;497-76-7 manufacturer.
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