Axitinib manufacturer CAS:319460-85-0
Sep 9th, 2022 at 23:46 Flavors & Fragrances Jessup 56 views Reference: Volej25RejN
Location: Jessup
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Applications: Axitinib is a multi-target tyrosine kinase inhibitor, inhibiting VEGFR1, VEGFR2, VEGFR3, PDGFRβ with IC50 values of 4, 20, 4, 2 nM, respectively.
| Item | Specification USP35 | Result |
| Appearance | Pale-yellow to off-whitepowder | Off white powder |
| Solubility | Soluble in dilute hydrochloric acid and dimethyl sulfoxide, slightly soluble in N, Ndimethylformamide, very slightly soluble in methanol or acetonitrile, almostinsoluble in water. | Complies |
| Identification | UV | Complies |
| HPLC | Complies | |
| Related Substances | Individual impurity:≤0.2% | 0.10% |
| Total impurities:≤1.0% | 0.33% | |
| Loss on drying | ≤1.0% | 0.45% |
| Residue on ignition | ≤0.1% | 0.06% |
| Heavy Metals | ≤20ppm | Complies |
| Assay | 98.0%- 102.0% | 99.96% |
| Conclusion : | Complies with Enterprise standard | |
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Inno Pharmchem (Pharmaceutical Intermediates Manufacturers in China) is exclusively focusing on the manufacturing of API's Intermediates, such as axitinib, cas:319460-85-0 , Axtinib and so on. We have helped clients businesses by scaling up its pharmaceutical products through the development of innovative processes and optimizing the production process thus it making it cost-efficient.
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