Fmoc-L-Trp(Boc) manufacturer CAS:143824-78-6
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Chemical Name: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
CAS.NO:143824-78-6
Molecular Formula: C31H30N2O6
Molecular Weight: 526.58000
Synonyms:
N(in)-Boc-Nalpha-Fmoc-L-tryptophan
Fmoc-L-Trp(Boc)
Nα-[(9H-Fluoren-9-ylMethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan
L-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
(2S)-3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid
Fmoc-Trp(tert-butyloxycarbonyl)-OH
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan
N(in)-Boc-Nα-Fmoc-L-Tryptophan
Nα-Fmoc-N(in)-Boc-L-Tryptophan
N1-Boc-Nα-Fmoc-L-tryptophan
L B656 HHJ H1OVMYVQ1- DT56 BNJ BVOX1&1&1 &&L or S Form
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-tryptophan
Fmoc-L-Trp(Boc)-OH
N-Fmoc-NIn-Boc-L-trp
N-(9-fluorenyl)methoxycarbonyl-Trp(Boc)-OH
Nalpha-Fmoc-N(in)-Boc-L-tryptophan
1-(tert-Butoxycarbonyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
Physical and Chemical Properties:
Density: 1.28 g/cm3
Boiling point: /
Melting point: 86 - 90ºC
Flash point:/
Refractive index:1.649
Specification:
Appearance: White to Off-white crystalline powder
Purity:≥99%
Moisture Content: ≤0.2%
Impurity: ≤0.2%
Loss on drying:≤0.50%
Packing:25 kg/drum, can also be packaged according to customer requirements
Storage:Store at 2-8ºC.Keep the container tightly closed, put it in a tight dispenser, and store in a cool, dry place.
Application:Fmoc-Trp(Boc)-OH is a very useful synthetic intermediates. It is used to prepare Trp containing-peptides.
| Items of Analysis | Standard of Analysis | Test Results |
| Appearance | White to off-white powder | Off-white powder |
| Optical rotation | -19.0±2.0°(C=1, in MDF) | -19.5° |
| Solubility | 1g in 10ml DMF clearly soluble | Clearly soluble |
| Moisture | ≤2.0% | 0.44% |
| Assay free amino acid | ≤0.2% | Conform |
| Purity | ≥99.0% | 99.61% |
| Max single unknown impurity | ≤0.3% | 0.07% |
| Fmoc-Osu | ≤0.1% | 0.06% |
| HOSU | ≤0.1% | ND |
| Fmoc-Trp-OH | ≤0.3% | 0.08% |
| Fmoc-β-Ala-OH | ≤0.1% | 0.01% |
| Fmoc-β-Ala-Trp(Boc)-OH | ≤0.1% | 0.01% |
| Fmoc-Trp(Boc)-Trp(Boc)-OH | ≤0.1% | 0.01% |
| Fmoc-OH | ≤0.1% | 0.02% |
| H-Trp(Boc)-OH | ≤0.1% | ND |
| Enantiomeric purity | ≤0.1% | 0.01% |
| Assay | ≥92.0% | 92.86% |
| Residual solvent | ≤8.0% | 4.26% |
| Ethyl acetate | ≤0.5% | 0.19% |
| EtOH | ≤0.5% | ND |
| MeOH | ≤0.3% | ND |
| Acetate | ≤0.02% | ND |
| Conclusion | Conforms to Factory Standard | |
Please visit our website if you have any inquiry: 2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid.If you can't find materials from around the world, please let us know and we will research and produce them in our labs equipped with high technology.
Inno Pharmchem (Pharmaceutical Intermediates Manufacturers in China) is exclusively focusing on the manufacturing of API's Intermediates, such as Fmoc-L-Trp(Boc), cas:143824-78-6 , Nalpha-(9H-Fluoren-9-ylmethoxy)carbonyl-N1-tert-butoxycarbonyl-L-tryptophan and so on. We have helped clients businesses by scaling up its pharmaceutical products through the development of innovative processes and optimizing the production process thus it making it cost-efficient.
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