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11-(1-Piperazinyl)-Dibenzo[b,f][1,4]Thiazepine Dihydrochloride manufacturer CAS:111974-74-4

Sep 9th, 2022 at 22:44   Material Chemicals   Mount Greenwood   54 views Reference: rlNbWnwQayg

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Chemical Name:11-(1-Piperazinyl)-Dibenzo[b,f][1,4]Thiazepine Dihydrochloride
CAS.NO:111974-74-4
Synonyms:11-(1-Piperazinyl)-Dibenzo[b,f][1,4]Thiazepine Dihydrochloride
11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride
Physical and Chemical Properties:
Boiling Point513.3ºC at 760 mmHg
Melting Point180-184°C
Molecular FormulaC17H19Cl2N3S
Molecular Weight368.324
Flash Point264.3ºC
Specification:
Appearance:White or almost-white powder
Assay:≥99.0%
Moisture:≤5.0%
ROI:≤1.0%
Piperazine content(TLC):≤0.2%
N,N-Dimethylaniline:≤45ppm
Thiazepine:≤0.30%
DBTP-thiazepine:≤0.50%
DBTP-ethyl:≤0.06%
Any unspecified:≤0.20%
Chloromethane:≤200ppm
Toluene:≤100ppm
Chloroform:≤100ppm
Chloroethane:≤200ppm
Packing:25 kg/drum, can also be packaged according to customer requirements
Storage:Store in a cool, ventilated place
Application:Intermediates of Quetiapine fumarate(CAS:111974-72-2).

Subjects Specifications Results
Description White or almost-white powder White powder
Identification HPLC Conforms
Water(KF) NMT 5.0% 2.54%
ROI NMT 1 .0% 0.11 %
Piperazine content(TLC) NMT0.2% Conforms
N,N-Dimethylaniline NMT45ppm Conforms
Related substances(HPLC)
Thiazepine NMT 0.30% 0.06%
DBTP-thiazepine NMT 0.50% 0.15%
DBTP-ethyl NMT 0.06% ND
Any unspecified NMT 0.20% 0.10%

Residual solvents
Chloromethane NMT 200ppm 101ppm
Toluene NMT100ppm 15pm
Chloroform NMT100ppm 38ppm
Chloroethane NMT200ppm 114ppm
Purity NLT 99.0% 99.62%
Conclusion Conforms to Factory Standard



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